In a letter noting the positive test, Dr. Kevin O’Connor, the White House physician, said Sunday that the president “continues to feel well” and will continue to work from the executive residence while in isolation. Biden tested positive on Saturday, requiring him to cancel travel and personal events as he will self-isolate for at least five days, according to Centers for Disease Control and Prevention guidelines. After initially testing positive on July 21, Biden, 79, was treated with the antiviral drug Paxlovid. He tested negative for the virus last Tuesday and Wednesday, prompting him to leave isolation wearing a mask indoors. Research suggests that a minority of those prescribed Paxlovid experience a rebound of the virus. The fact that a recovery and not a re-infection probably occurred is a positive sign for Biden’s health once he is cleared of the disease. “The fact that the president has cleared his illness and is symptom-free is a good sign and makes it less likely that he will develop long-term COVID,” said Dr. Albert Ho, an infectious disease expert at Yale University’s school of public health.